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Chirality modifies the interaction between knots
- Autor(en)
- Saeed Najafi, Luca Tubiana, Rudolf Podgornik, Raffaello Potestio
- Abstrakt
In this study we consider an idealization of a typical optical tweezers experiment involving a semiflexible double-knotted polymer, with steric hindrance and persistence length matching those of dsDNA in high salt concentration, under strong stretching. Using exhaustive molecular-dynamics simulations we show that not only does a double-knotted dsDNA filament under tension possess a free-energy minimum when the two knots are intertwined, but also that the depth of this minimum depends on the relative chirality of the two knots. We rationalize this dependence of the effective interaction on the chirality in terms of a competition between chain entropy and bending energy.
- Organisation(en)
- Computergestützte Physik und Physik der Weichen Materie
- Externe Organisation(en)
- Max-Planck-Institut für Polymerforschung, University of Ljubljana
- Journal
- Europhysics Letters
- Band
- 114
- Anzahl der Seiten
- 6
- ISSN
- 0295-5075
- DOI
- https://doi.org/10.1209/0295-5075/114/50007
- Publikationsdatum
- 06-2016
- Peer-reviewed
- Ja
- ÖFOS 2012
- 106006 Biophysik
- Schlagwörter
- Link zum Portal
- https://ucrisportal.univie.ac.at/de/publications/ffec8c60-924f-4e2f-951f-b42dee0cd99c