Non-monotonous polymer translocation time across corrugated channels

Autor(en)

Valentino Bianco, Paolo Malgaretti

Abstrakt

We study the translocation of polymers across varying-section channels. Using systematic approximations, we derive a simplified model that reduces the problem of polymer translocation through varying-section channels to that of a point-like particle under the action of an effective potential. Such a model allows us to identify the relevant parameters controlling the polymer dynamics and, in particular, their translocation time. By comparing our analytical results with numerical simulations we show that, under suitable conditions, our model provides reliable predictions of the dynamics of both Gaussian and self-avoiding polymers, in two-and three-dimensional confinements. Moreover, both theoretical predictions, as well as Brownian dynamic results, show a non-monotonous dependence of polymer translocation velocity as a function of polymer size, a feature that can be exploited for polymer separation.

Organisation(en)

Computergestützte Physik und Physik der Weichen Materie

Externe Organisation(en)

Universitat Autònoma de Barcelona , Max Planck Institut für Intelligente Systeme, Universität Stuttgart

Journal

Journal of Chemical Physics

Band

145

Anzahl der Seiten

13

ISSN

0021-9606

DOI

https://doi.org/10.1063/1.4961697

Publikationsdatum

09-2016

Peer-reviewed

Ja

ÖFOS 2012

106006 Biophysik, 103023 Polymerphysik, 103029 Statistische Physik, 103018 Materialphysik

Schlagwörter

ASJC Scopus Sachgebiete

Allgemeine Physik und Astronomie, Physical and Theoretical Chemistry

Link zum Portal

https://ucrisportal.univie.ac.at/de/publications/8bad3d10-c39c-4063-b03b-5836ba2a9d45