Dispersion-cancelled biological imaging with quantum-inspired interferometry

Autor(en)

Michael Mazurek, Kurt M. Schreiter, Robert Prevedel, Rainer Kaltenbaek, Kevin J. Resch

Abstrakt

Quantum information science promises transformative impact over a range of key technologies in computing, communication, and sensing. A prominent example uses entangled photons to overcome the resolution-degrading effects of dispersion in the medical-imaging technology, optical coherence tomography. The quantum solution introduces new challenges: inherently low signal and artifacts, additional unwanted signal features. It has recently been shown that entanglement is not a requirement for automatic dispersion cancellation. Such classical techniques could solve the low-signal problem, however they all still suffer from artifacts. Here, we introduce a method of chirped-pulse interferometry based on shaped laser pulses, and use it to produce artifact-free, high-resolution, dispersion-cancelled images of the internal structure of a biological sample. Our work fulfills one of the promises of quantum technologies: automatic-dispersion-cancellation interferometry in biomedical imaging. It also shows how subtle differences between a quantum technique and its classical analogue may have unforeseen, yet beneficial, consequences.

Organisation(en)

Department für Strukturbiologie und Computational Biology, Quantenoptik, Quantennanophysik und Quanteninformation

Externe Organisation(en)

University of Waterloo (UW)

Journal

Scientific Reports

Band

3

Anzahl der Seiten

5

DOI

https://doi.org/10.1038/srep01582

Publikationsdatum

2013

Peer-reviewed

Ja

ÖFOS 2012

103026 Quantenoptik, 103008 Experimentalphysik, 210006 Nanotechnologie, 103025 Quantenmechanik

Link zum Portal

https://ucrisportal.univie.ac.at/de/publications/8a1f3a90-cce3-4a6a-8285-5ccdd14dbc7f